As of Wednesday, March 24, 2021, Montana reports 103,666 confirmed COVID-19 cases, with 214 new cases reported in the last day: 36 in Cascade County, 32 in Gallatin County, 30 in Big Horn County, 29 in Yellowstone County, 23 in Missoula County, and more new cases in 19 more Montana counties. The number of active coronavirus cases in Montana is 898. Currently, 59 people are being treated in Montana hospitals for COVID-19. The most active cases are in Gallatin, Missoula, and Yellowstone Counties. 1,431 people have died in Montana of COVID-19. Twelve more deaths have been reported in the last day. Nationwide, more than 544,000 Americans have died of COVID-19. There have been 30,000,000 cases of coronavirus in the US, and counting.

Missoula County has reported two cases of the California COVID-19 variant in the county. It is uncertain if the people infected with this variant travelled out-of-state or if they caught the coronavirus variant locally. The Missoula City-County Health Department says that Missoula is also seeing an increase in COVID-19 cases with an increase of test positivity by 2-percent in the last week and an increase in the COVID-19 prevalence rate. There are more reported hospitalizations within younger groups of people in Missoula County, with more hospitalized patients in their 20s.